Facial PRP Treatment in North Cyprus

PRP's most distinctive quality is that it is autologous — derived entirely from the patient's own body. It is not a synthetic gel, an animal-derived protein or a laboratory-manufactured molecule. This matters in several ways:

• No allergy risk. An allergic reaction to your own blood product is biologically unexpected.
• No risk of granuloma or late-onset nodules. These complications seen with permanent synthetic fillers do not apply to PRP.
• Complete bodily compatibility. The cellular content and fluid balance are identical to your own.
• High safety profile. When single-use closed-system kits and a calibrated centrifuge are used, the risk of contamination is minimal.

However, this safety profile does not mean PRP is a miracle treatment. It is a biological therapy; results are gradual, not long-term in the permanent sense, and individual responses vary. Honest communication about PRP means this: it does not deliver the immediate volume a synthetic filler provides, but it supports the skin's own regenerative capacity.

PRP and mesotherapy are two treatments that are frequently confused. Both involve injections beneath the skin surface using fine needles; both aim at skin renewal. But the substance injected is entirely different — and the choice between them depends on that distinction.

• PRP: An autologous (biological) platelet concentrate obtained from the patient's own blood by centrifugation. Active agents: growth factors (PDGF, TGF-β, VEGF, etc.). Mechanism: stimulating the skin's own repair cascade.
• Mesotherapy: A synthetic or semi-synthetic cocktail formulated in a laboratory; typically containing hyaluronic acid, B-complex vitamins, amino acids, trace elements and skin renewal agents. Mechanism: delivering the building blocks the skin needs directly into the tissue.

There is no single answer to which is better:

• For younger skin with early-stage loss of vitality, mesotherapy is often sufficient and more cost-effective.
• Where collagen support and tissue repair are the priority — acne scarring, under-eye discolouration, post-surgical recovery — PRP is more targeted.
• Combination protocols are used in some clinics; both PRP and a hyaluronic acid-based mesotherapy product may be applied within the same session. We make this decision together at consultation.

In brief: mesotherapy brings building blocks from outside; PRP activates your body's own factory. There are areas where they overlap and areas where they do not replace each other.

"Vampire facial" is a term heard frequently in the media and serves as a familiar reference point for many patients. In reality it is a marketing name made viral by a celebrity's social media post — in terms of content, it describes a PRP combined with microneedling. In medical literature, the equivalent is "PRP with microneedling" or "PRP-augmented collagen induction therapy".

If the term feels more familiar to you, you are in the right place — we offer this protocol at Nis Clinic. We prefer not to use "vampire" as a heading, however; this is a medical procedure and deserves a clinical rather than marketing frame. Whatever it is called, the treatment is the same: blood collection → centrifugation → PRP absorbed into the micro-channels opened in the skin by microneedling.

Consultations are available in person at our clinic or online via WhatsApp or Zoom. During this appointment, skin assessment, identification of target areas (full face, under-eye, acne-scarred zones, etc.) and medical history review progress together. The topics we cover include:

• Your current medications: In particular, anticoagulants (aspirin, clopidogrel, warfarin, NOACs), NSAIDs, fish oil and high-dose vitamin E affect platelet function and can reduce PRP quality. You will be asked to discontinue aspirin and NSAIDs at least seven days beforehand with your prescribing doctor's agreement.
• Active infection: If there is active herpes, an acne abscess or folliculitis in the treatment area, the session is postponed.
• Blood disorders: Thrombocytopaenia (low platelet count), coagulopathy and uncontrolled platelet dysfunction are contraindications for PRP.
• Cancer treatment: Patients receiving active oncological treatment are not treated; oncologist approval is required.
• Pregnancy and breastfeeding: Contraindicated (detailed below).
• Hydration: Arriving dehydrated or having taken insufficient fluids on the day of blood collection makes venous access more difficult and affects PRP concentration. Adequate fluid intake the evening before and the morning of treatment is recommended.

At the end of the consultation, a written summary is shared, covering which areas are recommended for treatment, how many sessions, an indicative price and possible combinations (PRP alone, PRP with microneedling, PRP with mesotherapy, etc.).

On the day of treatment, the clinical sequence is as follows:

• Blood collection: Using a routine venous blood draw from your arm, 15–20 ml (approximately two to three small tubes) of blood is collected into a specialist PRP kit tube. The kit contains an anticoagulant and a separating gel; a closed-system setup is required to ensure clean separation of cellular layers and to prevent contamination.
• Centrifugation: The tube is spun in a calibrated medical centrifuge at a specific speed and duration (typically 10–15 minutes). The blood separates into three layers: red blood cells at the bottom, the buffy coat (platelet-rich intermediate layer) in the middle, and plasma at the top. The platelet-rich plasma is extracted from this middle layer together with a portion of the upper plasma.
• Ready PRP: The purified liquid obtained contains 3–5 times more platelets than the patient's whole blood. This fraction is ready for injection.

The entire process takes place in the same clinical room, without interruption. The blood is not transported elsewhere, left standing or mixed with another patient's tubes. You are entitled to see the batch number and expiry date of the kit; we share this on request.

Once PRP is prepared, treatment begins. At Nis Clinic it can be applied via two main techniques; the choice depends on the target area and the decision made at consultation.

1) Micro-injection (classic PRP application with MP Gun): The skin is cleansed and a topical anaesthetic cream is applied for 15–20 minutes. At Nis Clinic, injections are delivered using an MP Gun (automated mesotherapy device) — a 30-gauge fine-tip needle, fixed depth and standardised dose per shot; compared with manual injection this produces more homogeneous distribution, a shorter session and reduced discomfort. Small injections are made in a grid pattern across the designated area (full face, under-eye, upper cheek, etc.). A typical session involves 40–80 small puncture points; with topical anaesthesia most patients report minimal discomfort.

2) Microneedling with PRP (combination): Again following topical anaesthesia, a motor-driven microneedling device creates controlled micro-channels in the skin. PRP is applied topically to these channels and is both absorbed into the skin surface and supported with superficial injections. Microneedling mechanically initiates collagen stimulation; the biological signal from PRP amplifies this stimulus. Microneedling is preferred for skin with acne scarring or rough texture.

In both techniques the total time at the clinic is 45–60 minutes (blood draw + centrifugation + anaesthesia + treatment). You remain awake and seated throughout; once the session ends, mild redness and pinpoint bumps are visible, largely subsiding within 24 hours.

Practical guidelines for the first 24 hours after treatment:

• Avoid make-up — allow 24 hours for the fine needle punctures to close and eliminate infection risk.
• Do not wash the treated area with harsh soap; use lukewarm water and a gentle cleanser.
• Sun exposure, saunas, steam rooms and high-heat environments are not recommended for the first 48 hours.
• Avoid strenuous exercise for 24 hours.
• Anticoagulant medications should remain paused for a further few days with your doctor's agreement.

The skin returns to its normal daily routine after these 24 hours; arnica cream and a cold compress are recommended for patients who experience bruising or persistent redness.

PRP is not a treatment that produces a noticeable change in a single session — it is a course of treatment. A typical facial PRP programme is structured as follows:

• Initial course: 3–4 sessions, spaced four weeks apart. The interval between sessions is not shortened; collagen stimulation requires time to establish itself in the tissue.
• Maintenance: After the initial 3–4 sessions, a booster session every 6–12 months is recommended to sustain the effect. This interval is adjusted according to the individual's biology, age and skin condition.

The timeline for visible results is gradual:

• First 2 weeks: The skin begins to look slightly brighter and retain moisture better. This early change is largely the result of mechanical stimulation and hydration — not yet a collagen response.
• Weeks 3–6: Skin texture softens and tone begins to even out. The first visible changes appear in this window.
• Months 1–3: The real PRP effect occurs in this window. The collagen production response matures; softening of fine lines, lightening of under-eye discolouration and improvement in skin texture become noticeable.
• Months 3–6: If all sessions have been completed, the peak effect falls within this period.
• Months 6–12: The effect gradually begins to diminish; a maintenance session sustains it.

Unlike "I looked amazing two days later" stories, this is the honest account of PRP: a biological treatment on a biological timeline.

• Age 25+, preventive skin care: Suitable for younger patients who do not yet show marked signs of ageing but wish to maintain skin vitality and support collagen production.
• Fine lines and loss of skin texture: Expression lines forming at the surface, reduced brightness and elasticity.
• Acne scars (atrophic, moderate depth): An established indication for post-acne pitted scarring, particularly in combination with microneedling. The collagen remodelling process can reduce scar depth over repeated sessions.
• Dark circles (under-eye discolouration): PRP may contribute meaningfully to skin thickening and tone balance in vascular dark circles (blood vessels visible through thin skin) and those caused by thin skin and tissue loss. Limitation: PRP is not a solution for under-eye bags caused by fat herniation — surgical assessment (blepharoplasty) is required in those cases. For pigmented (melanin-related) discolouration, the effect of PRP is limited; pigmentation treatment protocols are more appropriate.
• Post-surgical recovery support: Following procedures such as rhinoplasty, facelift or blepharoplasty, PRP may be applied during the recovery period to support tissue repair — always in coordination with the operating surgeon.
• Enlarged pores and superficial skin roughness: Improvement in skin texture uniformity may be achieved.
• Mild to moderate skin laxity: PRP does not replace surgery on its own, but may be considered for early-stage tissue support.

In the following situations, PRP is not performed or requires careful individual evaluation:

• Pregnancy: Contraindicated. PRP is not offered during pregnancy due to the principle of avoiding elective cosmetic procedures in pregnancy and the absence of sufficient clinical safety data.
• Breastfeeding: Contraindicated. Treatment is deferred until breastfeeding has ended.
• Thrombocytopaenia and coagulopathy: Conditions with low platelet count (ITP, bone marrow suppression, certain drug effects) directly compromise the quality of PRP produced. Clotting disorders (haemophilia, Von Willebrand disease) are also contraindications.
• Active cancer treatment: Treatment is not performed during chemotherapy or radiotherapy. Patients who have completed cancer treatment may be assessed with oncologist approval.
• Systemic infection and sepsis risk: Treatment is deferred in the presence of active bacteraemia, viral infection or generalised systemic infection.
• Active skin infection in the treatment area: Conditions such as herpes simplex activation, acne abscess or impetigo must resolve before treatment can proceed.
• Uncontrolled chronic illness: In cases such as decompensated diabetes, renal failure or liver disease, assessment by the relevant specialist is required.
• Anticoagulant and antiplatelet therapy: Because platelet function is affected, the decision to pause medication is made jointly with the treating physician; proceeding with an elective treatment is not mandatory.
• Body dysmorphic disorder and unrealistic expectations: PRP is a biological, gradual supportive treatment — it does not replace surgical solutions. Expectation management is part of every consultation.
• Under 18: Not offered for cosmetic purposes.

Saying "no" to a candidacy assessment is not a lost opportunity for us — it is a necessary decision in the interest of genuine treatment efficacy and patient safety.

PRP is offered in practice at a wide range of facilities, from chain clinics to beauty centres. It is the protocol — not the signage — that determines treatment quality:

• Kit standard: We use CE-marked, closed-system, single-use PRP kits. Each patient's kit is individual; the batch number is recorded.
• Calibrated centrifuge: Our centrifuge undergoes calibration tracking and operates at specific speed and duration settings in accordance with the kit manufacturer's protocol. Non-calibrated devices or general-purpose laboratory centrifuges are not used.
• Sterile field: Skin antisepsis, sterile gloves, sterile draping and single-use instruments are standard practice. Blood collection and injection take place in the same room, without interruption.
• Dr. Meyzin's supervision: The treatment is performed by Op. Dr. İbrahim Meyzin directly or with his experienced clinical team under his supervision. Plastic surgery specialist training — facial anatomy, vascular mapping and surgical healing dynamics — provides a particularly meaningful advantage in sensitive areas such as the under-eye zone.

This protocol is not the standard across Northern Cyprus; we share these details openly so that you can make an informed choice.

Nis Clinic PRP pricing is determined by the treatment area and the combination protocol selected. We do not negotiate per unit; our fees are structured clearly by session and by package.

Indicative price ranges (Nis Clinic — 2026):

Price varies depending on the size of the target area, the kit used, whether microneedling is included and the number of sessions. All prices are confirmed after consultation; there are no hidden charges. Package pricing noticeably reduces the per-session cost — this does not mean any compromise in standards, which remain the same throughout.

PRP is a same-day, single-session treatment and does not require a medical tourism package. For patients planning a holiday, our Kyrenia clinic is well positioned for both consultation and treatment. PRP may be combined with a dermal filler treatment or mesotherapy for additional skin renewal goals; these decisions are made together at consultation.

PRP for hair loss requires a different protocol from facial PRP: injection depth, session intervals, supplementary pharmacological support (such as minoxidil or finasteride) and — critically — assessment of androgenetic alopecia stage all place hair PRP in a distinct medical framework. Facial PRP and hair PRP share the same biological principle but are two separate treatments.

For detailed information about hair PRP — session protocol, the role of PRP before and after hair transplantation, suitable candidates, session intervals and pricing — please visit our dedicated page: Hair PRP treatment.

This page focuses on facial, under-eye and skin tissue applications. If you have questions about hair PRP, the right resource is that page and a consultation with us.