Nis · Clinic

Department — Internal Medicine

Internal Medicine (General Medicine) Polyclinic

Diagnosis, treatment and long-term management of adult internal organ systems.

Nis Clinic's Internal Medicine department evaluates chronic and acute internal conditions in adult patients at polyclinic level. Diabetes, hypertension, thyroid disorders, kidney and liver function, and digestive complaints are among the primary areas of focus. In line with the specialty's traditional gatekeeper role, patients who require further input are referred — within the same building — to other departments at the clinic: General Surgery, Cardiology, and Gynaecology and Obstetrics. The department's lead physician appointment is currently in progress; during this period, content is published under Nis Clinic's editorial supervision. Case management is maintained through multidisciplinary joint review.

What Is Internal Medicine?

Internal medicine — also known as general medicine — is a broad specialty concerned with the non-surgical diagnosis and treatment of adult internal organ systems: cardiovascular, respiratory, digestive, endocrine, renal, haematological, rheumatological and infectious. After a patient's GP, the internal medicine polyclinic is often the first port of call; referrals to sub-specialties (cardiology, endocrinology, gastroenterology, etc.) are made from here when needed.

The most common reasons for attending our polyclinic include:

  • Uncontrolled blood pressure, palpitations, dizziness
  • Fatigue, weakness, weight changes — thyroid and diabetes screening
  • Digestive complaints — acid reflux, indigestion, constipation, abdominal pain
  • Interpretation of test results — blood tests, urine analysis, hormone panels
  • Routine health check-up and risk assessment
  • Chronic disease prescription renewal and long-term medication review

Our department's philosophy is to build an in-building network rather than relying on a single clinician. After an internal medicine assessment at Nis Clinic, a same-day joint consultation with Op. Dr. Alkan Küçük (General Surgery), Op. Dr. Ozan Emiroğlu (Cardiovascular Surgery), or Op. Dr. Çiğdem Çırpınar Mehmetoğlu on the women's health side can be arranged where clinically indicated.

Diabetes and Metabolic Conditions

Type 2 diabetes mellitus (DM), pre-diabetes, insulin resistance and obesity-related metabolic syndrome are among the most prevalent chronic conditions in the adult population of Northern Cyprus (TRNC). Our polyclinic manages patients with diabetes according to the following standards:

  • HbA1c (three-month average blood glucose) — the gold standard for assessing treatment effectiveness, typically measured every 3–6 months
  • Fasting and postprandial plasma glucose — acute monitoring and medication titration
  • Lipid panel — triglycerides, HDL, LDL and total cholesterol
  • Renal function tests — creatinine, eGFR, urinary microalbumin
  • Ophthalmology referral — annual retinopathy screening
  • Foot examination — peripheral neuropathy and vascular assessment

Each patient's individual HbA1c target is determined by considering age, duration of diabetes, co-existing conditions and hypoglycaemia risk; there is no single "ideal number". Lifestyle modification (diet and exercise) forms the foundation of every treatment plan; medication choices are built on top of that foundation. The decision to initiate insulin is based on response to oral agent combinations and acute complication risk — not HbA1c alone.

Patients in the pre-diabetes stage receive dedicated monitoring at our polyclinic. At this stage, lifestyle intervention can significantly reduce the risk of developing Type 2 DM; our standard is 3–6 months of active follow-up before considering pharmacotherapy.

Hypertension and Cardiovascular Risk Management

Hypertension (high blood pressure) is a silent condition affecting approximately one third of the adult population. Left untreated, it becomes the leading risk factor for cardiac, renal and cerebrovascular events. Our polyclinic manages hypertensive patients through the following steps:

  • Teaching correct measurement technique — home blood pressure monitoring, arm selection, rest requirements
  • 24-hour ambulatory blood pressure monitoring (Holter) referral where indicated
  • Secondary hypertension screening — particularly in young patients, resistant hypertension or sudden onset
  • Target organ damage assessment — ECG, renal function, microalbumin
  • Single-agent versus combination therapy — current guidelines generally favour early combination treatment
  • Lifestyle guidance — salt restriction, weight reduction, alcohol and smoking cessation, aerobic exercise

Hypertension management is a lifelong process; stopping or arbitrarily skipping medication is the most frequent cause of recurring complications. Patient education is therefore considered as valuable as the prescription itself. For comprehensive cardiovascular risk assessment — covering cholesterol, smoking history, family history and glucose tolerance — a joint review with Op. Dr. Ozan Emiroğlu (Cardiovascular Surgery) at our clinic can be arranged when appropriate; further cardiac investigation planning takes place under the same roof.

Thyroid Disorders and Nodule Assessment

Thyroid conditions are common in Northern Cyprus, partly due to dietary iodine patterns and genetic predisposition. Our polyclinic's thyroid assessment covers:

  • Hypothyroidism — fatigue, weight gain, cold intolerance, hair loss, low mood
  • Hyperthyroidism — palpitations, weight loss, heat intolerance, tremor, sleep disturbance
  • Subclinical thyroid dysfunction — TSH and T3/T4 discordance, monitoring decision
  • Thyroiditis (Hashimoto's, subacute thyroiditis) — antibody profiling for differential diagnosis
  • Thyroid nodule assessment — ultrasound, TI-RADS classification, fine-needle aspiration (FNA) referral

Dose adjustment during thyroid hormone replacement therapy (levothyroxine) requires patience: once blood levels have stabilised over 4–6 weeks, annual follow-up is generally sufficient. A sudden change in TSH is more likely to reflect medication compliance, food interaction (calcium, iron, soya) or pregnancy than an incorrect dose — and warrants investigation on that basis.

For patients with a thyroid nodule, the management decision is made using ultrasound + TSH + FNA cytology together, rather than any single test. Patients for whom surgical intervention is indicated — suspicious cytology, compressive symptoms, or cosmetic concern — are referred for joint assessment with Op. Dr. Alkan Küçük (General Surgery) from our polyclinic. When advanced endocrine specialist input is required, appropriate referral is arranged.

Chronic Disease Management — Lungs, Kidneys, Liver, Anaemia

The core of an internal medicine polyclinic is the balanced, long-term management of conditions that may last many years. Presentations we encounter regularly in this group include:

  • COPD and chronic bronchitis — spirometry referral, smoking cessation planning, exacerbation management and respiratory medicine consultation when required
  • Chronic kidney disease (CKD) — eGFR staging, proteinuria monitoring, renal damage related to hypertension and diabetes; nephrology referral in advanced stages
  • Liver function impairment — elevated AST/ALT, non-alcoholic fatty liver disease (NAFLD), viral hepatitis screening, assessment of alcohol-related damage
  • Anaemia — differential diagnosis of iron, B12 and folate deficiency; menstrual blood loss or anaemia of chronic disease; haematology consultation when further investigation is required
  • Osteoporosis risk assessment — DXA referral in postmenopausal women, vitamin D and calcium monitoring
  • Fatigue syndrome — systematic exclusion of sleep disorders, thyroid dysfunction, anaemia, depression and chronic infection

Our approach is to follow the patient through a single management record rather than sending them to a different specialist for each complaint. Annual health check-ups and 3–6 monthly review appointments are the simplest way to identify chronic conditions before they become uncontrolled.

Adult Vaccination and Preventive Health

Vaccination is not solely a childhood concern: in adult life, recommended vaccinations can prevent a significant proportion of deaths from infectious disease. Adult vaccinations available through our polyclinic include:

  • Seasonal influenza (flu) vaccine — recommended every autumn for those aged 65 and over, pregnant women, and patients with chronic lung disease, heart disease or diabetes
  • Pneumococcal vaccine — for those aged 65 and over, or with COPD, heart failure or immunosuppression; sequential PCV13 + PPSV23 schedule
  • Tetanus–diphtheria (Td) booster — every 10 years; earlier if required following injury
  • Shingles (herpes zoster) vaccine — two-dose recombinant schedule for adults aged 50 and over
  • Hepatitis B vaccine — healthcare workers, patients with chronic liver disease, those with a history of high-risk exposure
  • HPV vaccine — for women and men within the appropriate age range who have not previously been vaccinated
  • Travel vaccines — planned according to destination (yellow fever, typhoid, hepatitis A)

The vaccination decision is individualised based on the patient's age, co-existing conditions, current medications (particularly immunosuppressants) and prior vaccination records. In Northern Cyprus, adult vaccination is arranged through private health units; at our polyclinic, the prescription and administration plan are created together, with referral provided for vaccine procurement as needed.

Other components of preventive health — cancer screening (colonoscopy, mammography, cervical smear), bone density, vision and hearing — are monitored within the same patient record. Patients seeking a systematic check-up programme are welcome to visit our comprehensive health check-up page.

Frequently Asked Questions

How often should I attend a routine internal medicine review?
For a healthy adult, once a year is a reasonable starting frequency for a comprehensive internal medicine assessment. For those aged over 40, with a family history of chronic disease, who smoke, or who are overweight, a brief review every 6 months may be advisable. For patients already diagnosed with a chronic condition such as Type 2 diabetes, hypertension or a thyroid disorder, review frequency is every 3–6 months depending on whether the condition is stable. We determine the appropriate frequency based on your individual risk profile rather than a single rule.
What does an HbA1c test show, and how often should I have one?
HbA1c (glycated haemoglobin) reflects your average blood glucose level over approximately the past 3 months. Unlike a fasting glucose reading, it is not affected by daily fluctuations, making it the gold standard for diagnosing diabetes and assessing treatment effectiveness. A level of 6.5% or above is the accepted threshold for a diabetes diagnosis; the range of 5.7–6.4% is considered pre-diabetes. In patients with a confirmed diabetes diagnosis, HbA1c is measured every 3 months (following a treatment change) or every 6 months once the condition is stable.
Will I need to take blood pressure medication for the rest of my life?
It is important to be clear that, in most cases, hypertension management is a lifelong process; medications do not cure high blood pressure — they keep it under control. In some situations, however — particularly with significant weight loss, salt restriction, stopping alcohol and taking regular exercise — blood pressure may return to a normal range; in these patients, dose reduction or careful withdrawal of medication under medical supervision may be considered. Stopping medication on your own initiative is the most frequent cause of complications; when blood pressure becomes uncontrolled, the heart, kidneys and cerebral blood vessels are at risk of damage. If you wish to discuss a change, please raise it at your next appointment.
Which tests are used to assess thyroid function?
The first-line assessment typically involves TSH (thyroid-stimulating hormone); free T4 (fT4) and free T3 (fT3) are added where needed. If Hashimoto's thyroiditis is suspected, anti-TPO and anti-Tg antibodies are checked; in Graves' disease, TSH receptor antibody (TRAb) is measured. A palpable neck lump or a nodule found incidentally warrants thyroid ultrasound as standard; the decision regarding fine-needle aspiration (FNA) biopsy is made based on TI-RADS scoring. The tests required depend on the clinical presentation; routine "thyroid panel" packages are not always necessary.
Do I need medication to lower my cholesterol, or can lifestyle changes be enough?
The decision is based not on a single LDL value alone, but on your overall cardiovascular risk profile: age, sex, smoking history, blood pressure, diabetes and family history of early heart disease are all considered together. In low-to-moderate-risk patients with no history of heart disease, it is reasonable to try 3–6 months of lifestyle modification first (Mediterranean-style diet, 150 minutes of aerobic exercise per week, weight loss, smoking cessation). In high-risk patients — those with a history of coronary artery disease, diabetes or very high LDL — medications such as statins are started earlier. Concern about statins remains widespread; the real risk–benefit balance is assessed with figures at your review appointment.
What could be causing my persistent fatigue?
Chronic fatigue points to a wide range of possible causes rather than a single condition. At our polyclinic, we systematically work through the following possibilities: iron, B12 or folate deficiency anaemia, thyroid dysfunction, undiagnosed diabetes, vitamin D deficiency, obstructive sleep apnoea, depression and chronic infections. Medication side effects (particularly some antihypertensives and antihistamines) and inadequate sleep also make a significant contribution. In the majority of cases, a blood test, sleep questionnaire and lifestyle assessment together clarify the picture. Persistent fatigue with no identifiable cause requires further investigation.
Do I need to book an appointment to have my test results explained?
Yes — interpreting blood or imaging results based solely on "high/low" flags found online is not safe. The same laboratory value can carry a different clinical meaning depending on the context; for example, a mildly elevated liver enzyme may be significant in a patient taking certain medications, while a different interpretation applies in a physically active individual. Bringing your existing results with you (paper or PDF) when you attend our polyclinic speeds up the assessment. Appointments can be made by telephone or via our online booking form.
Are flu and pneumococcal vaccines really necessary for adults?
For adults with chronic lung disease, heart failure, diabetes, immunosuppression or those aged 65 and over, annual flu vaccination and pneumococcal vaccination at recommended intervals provide meaningful protection — reducing the risk of serious pneumonia and hospital admission. For healthy younger adults, the flu vaccine is recommended but not essential. The vaccination decision is made according to your individual risk profile; at your review appointment, we record your current vaccination status and plan the next steps together.

Editorial Review

Nis ClinicClinical Content Editor — Department lead physician appointment pending

Clinical Content Editor — Department lead physician appointment pending

Last reviewed:

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